SAE2 / UBA2 Recombinant Rabbit mAb

SAE2 / UBA2 Recombinant Rabbit mAb 

中文名称 : 泛素样蛋白SUMO2激活酶重组兔单抗

Catalog No.：DM-S4484 

Host: Rabbit 

Isotype: IgG

Clonality: Recombinant 

CloneNo.: 7F9

GeneID: 10054 

SWISS: Q9UBT2 

Target: SAE2 / UBA2

Immunogen: A synthesized peptide derived from human UBA2: 50-100/640. 

Purification: affinity purified by Protein A

Storage: 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. 

Background: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. 

Applications: WB (1:500-2000) IHC-P (1:50-200) IHC-F (1:50-200) IF (1:50-200) Flow-Cyt (1:50-100) IP (1:20-50)

Reactivity: Human, Mouse, Rat 

Predicted 71 kDa 

Observed 80 kDa 

Subcellular Location: Cytoplasm ,Nucleus