PDX1 Rabbit pAb

PDX1 Rabbit pAb 

中文名称 : 胰岛素促进因子/胰十二指肠同源异型盒蛋白抗体

Catalog No.：DM-S4476 

Host: Rabbit 

Clonality: Polyclonal 

GeneID: 3651 

Target: PDX1

Isotype: IgG

SWISS: P52945 

Applications: IHC-P (1:100-500) IHC-F (1:100-500) IF (1:100-500) Flow-Cyt (1μg/Test) 

Reactivity: Human, Mouse, Rat (predicted: Rabbit, Pig, Sheep, Cow, Chicken, Dog, Horse) 

Predicted 30 kDa 

Subcellular Location: Cytoplasm ,Nucleus 

Immunogen: KLH conjugated synthetic peptide derived from human PDX1: 101-200/284. 

Purification: affinity purified by Protein A

Concentration: 1mg/ml

Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development ofthe pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin- dependent diabetes mellitus (IDDM), as well as maturity onset diabetes ofthe young type 4 (MODY4). [provided by RefSeq, Aug 2017]