Elf-1 Polyclonal Antibody

Elf-1 Polyclonal Antibody 

Catalog No DM-01689 

Isotype IgG

Reactivity Human 

Applications WB;IHC;IF;ELISA 

Gene Name ELF1 

Protein Name ETS-related transcription factor Elf-1 

Immunogen The antiserum was produced against synthesized peptide derived from human ELF1. AA range:537-586 

Specificity Elf-1 Polyclonal Antibody detects endogenous levels of Elf-1 protein. 

Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. 

Source Polyclonal, Rabbit,IgG 

Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. 

Dilution Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. 

Concentration 1 mg/ml 

Purity ≥90% 

Storage Stability -20°C/1 year 

Synonyms ELF1; ETS-related transcription factor Elf-1; E74-like factor 1 

Observed Band 67kD 

Cell Pathway Nucleus. 

Tissue Specificity In fetal tissues, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it is highly expressed in pancreas, spleen, thymus and peripheral blood leukocytes, expressed at moderate levels in heart, placenta, lung, liver, skeletal muscle, kidney, prostate, ovary, small intestine and colon, and weakly expressed in brain and testis. 

Function function:Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Binds to the underphosphorylated form of RB. May interact with other transcription factors in order to regulate specific genes. Interacts with RUNX1.,tissue specificity:In fetal tissue, it is highly expressed in heart, lung liver and kidney, and weakly expressed in brain. In adult, it